Imagine a future where your doctor gives you a customized infusion with a top-up every 5 to 10 years that “dials down” your genetic risk factors for all kinds of diseases WITHOUT making permanent changes to your DNA. Welcome to the world of epigenetic editing …

What are the pathways to a more secure digital future? I asked Bruce Schneier, the biggest name in cybersecurity, about incentives, IoT laws, data decentralization, ransomware and cryptocurrencies, quantum computers, crypto-agility, continuous authentication and more …

For 41 of the past 49 days, the fifth largest economy in the world has met >100% of electricity demand using solar, wind and hydro generation, frequently exceeding 140% of demand. What lessons can be learned? What does this tell us about future of energy? I asked Prof. Mark Jacobson, the most respected renewables voice on the planet …

What will the global energy mix look like in 2060? Which technologies will dominate in future, and which will dead-end? What about the toughest problems, like powering long range ships and aircraft? What happens to nuclear? I asked Michael Barnard, consultant to the biggest energy investors on the planet ...

What does the future of medical devices look like when microchips and nervous systems speak the same language? I learned about the EXPONENTIAL opportunities from the inspiring Dr Elisa Donati, a senior scientist working at the intersection of neuroscience, technology and medicine …

Affordable age-reversal. Xenotransplants to eliminate organ shortages. Rewriting health economics. Virus resistant livestock and crops. What are the imminent genomics pathways to a better future? I asked George Church, the greatest genomic pioneer in the world …

GEORGE CHURCH: two things I'd like to see happen, is affordable healthcare to get us up out of poverty, and then something that will solve the 90% of disease that will get us past our normal retirement age. If we extend life by 30 years, and we extend retirement by 30 years, then …

The future of medicine is one where all cancers are either 100% curable or turned into manageable diseases. You’ve heard me tell the story in my keynotes for many years. Now it’s time for you to hear from one of the heroes of that story, Bruce Levine …

BRUCE LEVINE: The dream is that we will have in vivo therapies of many types. We're going to have them soon with sickle cell disease and perhaps some other hemoglobinopathies … I think we'll see in vivo CAR T-cells, whether that's an autoimmune disease or blood cancers … 

Will AI exacerbate inequality? Can we stop that from happening? As the world grapples with guardrails to protect us from future dangers of AI, I thought it timely to talk to an ethicist who has lived and breathed these challenges for decades. Enter, Wendell Wallach, Carnegie-Uehiro fellow at the Carnegie Council for Ethics in International Affairs …

WENDELL WALLACH: That's what really concerns people who see gender bias and racial bias and so forth: the ‘existential risk’ is sucking the air out of the room and it's not letting us address the near-term things that we could actually address. One of the things we could address is just making the bloody people who deploy these things accountable ...

The story of cancer medicine is multi-threaded. It’s a story of early detection, of surgical removal, of radio- and chemo-therapies, of understanding lifestyle factors, of sequencing and pinpointing genetic factors, and lately of immunotherapies, with each new weapon overlapping and complementing the others. Dr Ben Stanger and his team at the UPenn Perelman School of Medicine are working on 3 new entire armories …

BEN STANGER: The biggest impact I think in cancer will come not from treating cancer, but from preventing it from happening in the first place. So there is an emerging concept out there now called cancer interception. It's subtly different from prevention …

We all know someone who has died of a heart attack. That’s because heart disease is the number one killer on our planet today. At a cutting-edge facility at the University of Pennsylvania, Dr Kiran Musunuru is developing something truly extraordinary, a ‘one and done’ gene therapy to reduce heart disease across ALL of humanity …

KIRAN MUSUNURU: What if we could deploy those good mutations across the entire population? Basically what you're doing is you're shifting the entire bell curve [for heart disease]. There's still going to be people who are still at higher risk than the general average population, but they're much better off …

“I've never loved anyone the way I loved you,” Theodore Twombly tells Samantha, and Samantha, replies, “Me too. Now we know how.” It’s a soulful exchange from a beautiful movie – Her – and it leaves the viewer in no doubt that Theodore, played Joaquin Phoenix, is truly and deeply and go-to-sleep-dreamy, in love …

Insurance companies must deal with the financial realities of climate change. They must make quantitative decisions and translate risks into dollars. They must do it for today’s impacts and predicted future impacts. And behind the insurance companies are the reinsurance companies who act as shock absorbers to the industry on a global scale …

TRENT THOMSON: The frequency of those perils – wildfire, floods, storms – have gone up by about 450% over 30 years, for very large losses. And the severity of those events have gone up by 1,500%. And so, what's driving that? It's economic growth, it's the value of the assets. It's the urbanization, people wanting to live more in cities, around the world, and that concentration of risk ...

I’m calling neuromorphic computing the most important computer engineering research in the world, now and through the next 20 years. That’s right, more important than quantum computing (you heard it hear first!). Why? Because everything we want to do in the future of AI, everywhere we want to go long-term, is predicated on transitioning to …

ALEXANDRE MARCIREAU: So what really stands out I think for the brain is that it is a massively parallel 3D structure with those incredible connections. Part of the computation is in the very structure of the system. Ultimately, we'd like to build systems that are more like the brain …